A multiple antibiotic and serum resistant oligotrophic strain, Klebsiella pneumoniae MB45 having novel dfrA30, is sensitive to ZnO QDs.

PMID: 215958932011India

Key Findings

The study identifies a novel trimethoprim resistance gene, dfrA30, in the oligotrophic strain Klebsiella pneumoniae MB45, which confers high-level resistance to trimethoprim. The gene was functionally validated by cloning and susceptibility testing in E. coli JM109.

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4gene entries

0mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
dfrA30	2	dihydrofolate reductase	TrimethoprimTRIMETHOPRIM	Klebsiella pneumoniae Escherichia coli JM109 Klebsiella sp. MB45	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	-

Browse Papers

A multiple antibiotic and serum resistant oligotrophic strain, Klebsiella pneumoniae MB45 having novel dfrA30, is sensitive to ZnO QDs.

AMR Genes