Clitocine reversal of P-glycoprotein associated multi-drug resistance through down-regulation of transcription factor NF-κB in R-HepG2 cell line.

PMID: 229279012012

Key Findings

Clitocine reverses P-gp associated multidrug resistance by down-regulating NF-κB, leading to reduced MDR1 expression and increased sensitivity to doxorubicin.

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1gene entry

0mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
mdr1	1	P-glycoprotein (P-gp)	-	-	Reslit	-

Browse Papers

Clitocine reversal of P-glycoprotein associated multi-drug resistance through down-regulation of transcription factor NF-κB in R-HepG2 cell line.

AMR Genes