Reclaiming the efficacy of β-lactam-beta-lactamase inhibitor combinations: avibactam restores the susceptibility of CMY-2-producing Escherichia coli to ceftazidime.

PMID: 248200812014

Key Findings

Avibactam restores the susceptibility of CMY-2-producing Escherichia coli to ceftazidime by inactivating the CMY-2 beta-lactamase, demonstrating effective resistance reversal.

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5gene entries

0mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
blaCMY	2	beta-lactamase	CeftazidimeTICARCILLINCEPHALOSPORINAMOXICILLINCEFOXITINTICARCILLIN+CLAVULANIC ACIDAMPICILLIN+CLAVULANIC ACIDAMPICILLINCEFOTAXIME+4 more	Escherichia coli	Card DatabaseReference Gene CatalogResFinder DatabaseReslit

Browse Papers

Reclaiming the efficacy of β-lactam-beta-lactamase inhibitor combinations: avibactam restores the susceptibility of CMY-2-producing Escherichia coli to ceftazidime.

AMR Genes