Multi-drug carbapenem-resistant Klebsiella pneumoniae infection carrying the OXA-48 gene and showing variations in outer membrane protein 36 causing an outbreak in a tertiary care hospital in Riyadh, Saudi Arabia.
PMID: 252450012014
Key Findings
Under development. Phenotype should be used with caution.
0gene entries
44mutation entries
AMR Mutations
| Nucleotide Change | Gene | Protein Change | Effect | Type | Resistance To | Database | Status |
|---|---|---|---|---|---|---|---|
| - | ompK36 | S88G | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | A184M | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | F207W | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | Q227S | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | T254S | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | T86V | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | G183D | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | A93S | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | L191Q | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | N218H | - | - | Carbapenem | ResFinder | Not Validated |
| - | ompK36 | L229V | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | D51N | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | T222L | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | L229A | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | G183S | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | T200L | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | Q227N | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | S89T | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | A184P | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | A260V | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | D91K | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | A217S | - | - | Carbapenem | ResFinder | Not Validated |
| - | ompK36 | L228V | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | N304E | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | D49S | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | A190W | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | S354N | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | L59V | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | L191S | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | D223G | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | E232R | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | S90D | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | G189T | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | F207Y | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | L228K | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | ins131FGGD | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | F198Y | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | D224E | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | H235D | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | ins184GAL | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | ins311R | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | ins234P | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | ins131SG | - | - | Cephalosporins | ResFinder | Not Validated |
| - | ompK36 | ins234L | - | - | Cephalosporins | ResFinder | Not Validated |