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Key Findings
The study identified the presence of the aph(3')-Ic, aph(3")-Ib, aph(6)-Id, and aac(3)-XI genes in Corynebacterium striatum clinical isolates, which confer resistance to various aminoglycosides. These genes were detected through PCR and sequencing, and their association with resistance was confirmed by MIC testing.
| Gene Name | Alleles | Encodes | Confers Resistance To | Organisms | Database | Validation Status |
|---|---|---|---|---|---|---|
| aac(3)-XI | 1 | aminoglycoside 3-N acetyl transferase | GentamicinTobramycinSisomicin |
| Reslit | - |
| aph(3'')-Ib | 1 | aminoglycoside-3"-phosphotransferase | Streptomycin |
| Reslit | - |
| aph(3'')-Ic | 1 | aminoglycoside-O-phosphotransferase |
KanamycinNeomycin |
|
Reslit |
| - |
| aph(6)-Id | 1 | aminoglycoside-6-phosphotransferase | Streptomycin |
| Reslit | - |
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