An allelic variant of the PmrB sensor kinase responsible for colistin resistance in an Escherichia coli strain of clinical origin.

PMID: 286985682017

Key Findings

The pmrB gene was found to carry a novel mutation in the clinical isolate LC711/14, which was experimentally validated to confer colistin resistance.

0gene entries

2mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pmrB	-	T29C	loss of function	Escherichia coli, E. coli	Colistin	Reslit	-