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Genotoxic Agents Produce Stressor-Specific Spectra of Spectinomycin Resistance Mutations Based on Mechanism of Action and Selection in Bacillus subtilis.

PMID: 343392802021

Key Findings

Bacillus subtilis rpsE mutations conferring resistance to spectinomycin; CARD accession: CARD:3007527

0gene entries

16mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpsE	G83A	-	single resistance variant	Bacillus subtilis	Spectinomycin	Card Database	-
rpsE	R30P	-	-	Bacillus subtilis	Spectinomycin	Reslit	-
rpsE	G64C	-	single resistance variant	Bacillus subtilis	Spectinomycin	Card Database	-
rpsE	G86T	-	multiple resistance variants	Bacillus subtilis	Spectinomycin	Card Database	-
rpsB	L25F	-	-	Bacillus subtilis	Spectinomycin	Reslit	-
rpsE	G89C	G266T	single resistance variant	Bacillus subtilis	Spectinomycin	Card DatabaseReslit	-
rpsE	C88G	-	single resistance variant	Bacillus subtilis	Spectinomycin	Card Database	-
rpsE	A77T	-	single resistance variant	Bacillus subtilis	Spectinomycin	Card Database	-
rpsE	A67G	-	single resistance variant	Bacillus subtilis	Spectinomycin	Card Database	-
rpsE	C85G	-	single resistance variant	Bacillus subtilis	Spectinomycin	Card Database	-
rpsE	G73T	-	single resistance variant	Bacillus subtilis	Spectinomycin	Card Database	-
rpsE	G82T	-	multiple resistance variants	Bacillus subtilis	Spectinomycin	Card Database	-
rpsE	G83T	-	single resistance variant	Bacillus subtilis	Spectinomycin	Card Database	-
rpsE	G83C	-	single resistance variant	Bacillus subtilis	Spectinomycin	Card Database	-
rpsE	A78C	GCT->TGT	-	Bacillus subtilis	Spectinomycin	Reslit	-