Bedaquiline Drug Resistance Emergence Assessment in Multidrug-Resistant Tuberculosis (MDR-TB): a 5-Year Prospective In Vitro Surveillance Study of Bedaquiline and Other Second-Line Drug Susceptibility Testing in MDR-TB Isolates.

Key Findings

The study identified Rv0678 as a gene associated with bedaquiline resistance in MDR-TB isolates, with nonsynonymous nonsilent mutations in Rv0678 linked to reduced susceptibility to bedaquiline.

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1gene entry

0mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
Rv0678	1	protein	Bedaquiline	Mycobacterium tuberculosis	Reslit	-

Browse Papers

Bedaquiline Drug Resistance Emergence Assessment in Multidrug-Resistant Tuberculosis (MDR-TB): a 5-Year Prospective In Vitro Surveillance Study of Bedaquiline and Other Second-Line Drug Susceptibility Testing in MDR-TB Isolates.

AMR Genes