Proximal Binding Pocket Arg717 Substitutions in Escherichia coli AcrB Cause Clinically Relevant Divergencies in Resistance Profiles.

PMID: 353115212022

0gene entries

8mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
acrB	R717L	-	multidrug efflux RND transporter permease subunit AcrB	Escherichia coli, Salmonella enterica	Macrolide\|FluoroquinolonesAZITHROMYCIN/CLARITHROMYCIN/ERYTHROMYCIN	ReslitReference Gene Catalog	-
acrB	R717Q	-	multidrug efflux RND transporter permease subunit AcrB	Escherichia coli, Salmonella enterica	Macrolide\|FluoroquinolonesAZITHROMYCIN/CLARITHROMYCIN/ERYTHROMYCIN	ReslitReference Gene Catalog	-