FepR as a Central Genetic Target in the Adaptation to Quaternary Ammonium Compounds and Cross-Resistance to Ciprofloxacin in Listeria monocytogenes.

PMID: 356638782022

Key Findings

mutations in fepR lead to reduced DNA binding and overexpression of fepA, causing ciprofloxacin resistance

1gene entry

1mutation entry

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
fepR	1	transcriptional regulator	Ciprofloxacin	Listeria monocytogenes	Reslit	-

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
fepR	108fs	-	reduced DNA binding	Listeria monocytogenes	Ciprofloxacin	Reslit	-