Molecular analysis of AmpC-producing Escherichia coli isolated from pediatric patients.

PMID: 399027382025Japan

Key Findings

The study identified plasmid-mediated AmpC genes blaDHA-1 and blaCMY-2, as well as chromosomal ampC mutations in pediatric E. coli isolates, contributing to cephalosporin resistance.

View on PubMed

2gene entries

5mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
blaCMY	1	AmpC beta-lactamase	CeftazidimeCefotaximeCefepimeCefoxitin	Escherichia coli	Reslit	-
blaDHA	1	AmpC beta-lactamase	CeftazidimeCefotaximeCefepimeCefoxitin	Escherichia coli	Reslit

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
ampC	A292V	-	-	Escherichia coli	Ceftazidime\|Cefepime	Reslit	-
ampC	-	C17T	-	Escherichia coli	Ceftazidime\|Cefotaxime\|Cefepime\|Cefoxitin	Reslit	-
ampC	-	G-18A	-	Escherichia coli	Ceftazidime\|Cefotaxime\|Cefepime\|Cefoxitin

Browse Papers

Molecular analysis of AmpC-producing Escherichia coli isolated from pediatric patients.

AMR Genes

AMR Mutations