Proteostasis modulates gene dosage evolution in antibiotic-resistant bacteria.

PMID: 400730782025

Key Findings

Mutations in folA were found to confer resistance to trimethoprim.

0gene entries

6mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
folA	Y151D	-	-	Escherichia coli	Trimethoprim	Reslit	-
folA	W30R	-	-	Escherichia coli	Trimethoprim	Reslit	-
folA	-	A-64T	-	Escherichia coli	Trimethoprim	Reslit	-
folA	-	C-35T	-	Escherichia coli	Trimethoprim	Reslit	-