Association between baseline prevalence of mutations in BDQ candidate resistance genes, baseline phenotypic BDQ resistance, previous exposure to CFZ, and treatment outcomes

PMID: 402023352023Armenia

Key Findings

The study identified mutations in the Rv0678 gene as a significant factor in bedaquiline resistance among Mycobacterium tuberculosis isolates, with various frameshift mutations contributing to reduced susceptibility.

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1gene entry

0mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
Rv0678	1	putative membrane protein	Bedaquiline	Mycobacterium tuberculosis	Reslit	-

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Association between baseline prevalence of mutations in BDQ candidate resistance genes, baseline phenotypic BDQ resistance, previous exposure to CFZ, and treatment outcomes

AMR Genes