A novel mutation of ramR involved in tigecycline resistance in Klebsiella pneumoniae.

PMID: 403720272025

Key Findings

The mutation leads to a truncated RamR protein, reducing its ability to inhibit the AcrAB-TolC efflux pump.

0gene entries

1mutation entry

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
ramR	-	517_518del	reducing its ability to inhibit the AcrAB-TolC efflux pump	Klebsiella pneumoniae	Tigecycline	Reslit	-