Mechanism of AGA action in fusA mutant strains

PMID: 411623732022

Key Findings

The P610L mutation in fusA was shown to confer resistance to multiple aminoglycosides by reducing error cluster formation.

0gene entries

1mutation entry

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
fusA	P610L	-	selectively slow ribosome movement along mRNA when aminoglycosides are bound	Escherichia coli	Aminoglycoside	Reslit	-