Resistance, heteroresistance, and fitness costs drive colistin treatment failure during Acinetobacter baumannii pneumonia.

PMID: 414610322026

Key Findings

Both mutations are in the PmrB histidine kinase domain and contribute to colistin resistance.

0gene entries

2mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pmrB	A236E	-	-	Acinetobacter baumannii	Colistin	Reslit	-
pmrB	T235I	-	-	Acinetobacter baumannii	Colistin	Reslit	-