mprF

Validation StatusCandidate

Overview

Papers: 2
Mutations: 2

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
E44V	-	-	Staphylococcus aureus	daptomycin	Reslit	Candidate
-	C1264T	-	Staphylococcus aureus	daptomycin	Reslit	Candidate

Papers2

Activity of telavancin against staphylococci and enterococci determined by MIC and resistance selection studies.

PMID 19620338 · 2009

Mutation detected in daptomycin-resistant clones.

Mutation Information

mprF: p.E44V

Protein Change: E44V
Organisms: Staphylococcus aureus
Confers Resistance To: daptomycin
Source Database: Reslit

Evaluation of daptomycin pharmacodynamics and resistance at various dosage regimens against Staphylococcus aureus isolates with reduced susceptibilities to daptomycin in an in vitro pharmacodynamic model with simulated endocardial vegetations.

PMID 18591272 · 2008

Mutation in mprF promoter associated with reduced daptomycin susceptibility.

Mutation Information

mprF: c.C1264T

Nucleotide Change: C1264T
Organisms: Staphylococcus aureus
Confers Resistance To: daptomycin
Source Database: Reslit

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mprF

Mutations

Mutation Information

Mutation Information