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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations ramRA580T

GeneramR

Protein ChangeA580T

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: negative regulator of RamA, itself a transcriptional activator of the acrAB genes
Resistance To: Tetracycline
Organisms: Klebsiella pneumoniae
Papers: 1

Paper Information1

1

Genomic evolution of the globally disseminated multidrug-resistant Klebsiella pneumoniae clonal group 147.

PMID 35019836 · 2022

Mutation in ramR leads to increased resistance to tetracyclines.

Mutation Information

Protein Change: A580T
Organisms: Klebsiella pneumoniae
Confers Resistance To: Tetracycline

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Effect on Function

negative regulator of RamA, itself a transcriptional activator of the acrAB genes

Source Database

Reslit

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research