Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Mechanisms of polymyxin resistance: acquired and intrinsic resistance in bacteria.
Mutations in pmrB lead to constitutive activation of the pmrA/pmrB system, resulting in increased resistance to polymyxins.
pmrB
Molecular and genome characterization of colistin-resistant Escherichia coli isolates from wild sea lions (Zalophus californianus).
Mutations in pmrB and phoQ were identified but not confirmed to contribute to colistin resistance.
Whole-genome analyses of extended-spectrum or AmpC β-lactamase-producing Escherichia coli isolates from companion dogs in Japan.
associated with polymyxin resistance
Antimicrobial Resistance Profile and ExPEC Virulence Potential in Commensal Escherichia coli of Multiple Sources.
Acquisition of the mcr-1 Gene Lowers the Target Mutation to Impede the Evolution of a High-Level Colistin-Resistant Mutant in Escherichia coli.
Plasmid-mediated colistin resistance and ESBL production in Escherichia coli from clinically healthy and sick pigs.
Colistin in Pig Production: Chemistry, Mechanism of Antibacterial Action, Microbial Resistance Emergence, and One Health Perspectives.
Global colistin use: a review of the emergence of resistant Enterobacterales and the impact on their genetic basis.
Occurrence and Characterization of mcr-1-Positive Escherichia coli Isolated From Food-Producing Animals in Poland, 2011-2016.
mutation in the chromosomal pmrB gene
Genomic Characterization of Prevalent mcr-1, mcr-4, and mcr-5 Escherichia coli Within Swine Enteric Colibacillosis in Spain.
Genomic Characterization of Antibiotic Resistant Escherichia coli Isolated From Domestic Chickens in Pakistan.
Quinolone-resistant Escherichia coli at the interface between humans, poultry and their shared environment- a potential public health risk.
Single substitution
Polymorphism of genes encoding PmrAB in colistin-resistant strains of Escherichia coli and Salmonella enterica isolated from poultry and swine.
pmrB
Genetic analysis of colistin resistance in Salmonella enterica serovar Typhimurium.
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