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Browse Mutations parCK441I

GeneparC

Protein ChangeK441I

Nucleotide ChangeA1322T

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Fluoroquinolones
Organisms: Escherichia coli, Acinetobacter baumannii, Pseudomonas aeruginosa
Papers: 1

Paper Information1

1

BWC0977, a broad-spectrum antibacterial clinical candidate to treat multidrug resistant infections.

PMID 39294149 · 2024

Mutation Information

parC: p.K441I / c.A1322T

Protein Change: K441I
Nucleotide Change: A1322T
Organisms: Escherichia coli, Acinetobacter baumannii, Pseudomonas aeruginosa
Confers Resistance To: Fluoroquinolones

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

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Reslit

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research