ResLit - Antimicrobial Resistance Gene & Mutation Database

GeneampC

beta-lactamase

Protein ChangeT105A

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: more efficient carbapenem and cefepime hydrolysis
Resistance To: imipenem, ceftazidime, cefepime, aztreonam
Organisms: Pseudomonas aeruginosa
Papers: 2

Paper Information2

Within-host whole genome analysis of an antibiotic resistant Pseudomonas aeruginosa strain sub-type in cystic fibrosis.

Research Article

PMID 28273168 · 2017

Mutation Information

ampC: p.T105A

Protein Change: T105A
Organisms: Pseudomonas aeruginosa
Confers Resistance To: imipenemceftazidimecefepime
Validation Method: whole genome sequencing
Source Database: Reslit

Genetic Diversity of Multidrug-Resistant Pseudomonas aeruginosa Isolates Carrying bla (VIM-2) and bla (KPC-2) Genes That Spread on Different Genetic Environment in Colombia.

Research Article

PMID 34512563 · 2021

Mutation Information

ampC: p.T105A

Protein Change: T105A
Organisms: Pseudomonas aeruginosa
Confers Resistance To: ceftazidimeaztreonam
Effect on Function: more efficient carbapenem and cefepime hydrolysis
Validation Method: whole-genome sequencing
Source Database: Reslit

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