Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Perturbed structural dynamics underlie inhibition and altered efflux of the multidrug resistance pump AcrB.
Research Article
The G288D mutation affects the structural dynamics of the drug-binding pocket and alters substrate efflux.
Cryo-EM Structure and Molecular Dynamics Analysis of the Fluoroquinolone Resistant Mutant of the AcrB Transporter from Salmonella.
Research Article
The G288D mutation in AcrB is responsible for increased resistance to fluoroquinolones.
AcrB drug-binding pocket substitution confers clinically relevant resistance and altered substrate specificity.
Research Article
acrB
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