Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
A Molecular Perspective on Colistin and Klebsiella pneumoniae: Mode of Action, Resistance Genetics, and Phenotypic Susceptibility.
Mutations in PmrA/PmrB lead to constitutive activation of the arnBCADTEF operon and pmrC.
Genotyping of paired KPC-producing Klebsiella pneumoniae isolates with and without divergent polymyxin B susceptibility profiles.
Substitutions in PmrB were associated with polymyxin B resistance.
A nosocomial outbreak of colistin and carbapenem-resistant hypervirulent Klebsiella pneumoniae in a large teaching hospital.
Three missense mutations identified, T157P validated to increase colistin MIC
Prevalence and molecular characteristics of colistin-resistant isolates among carbapenem-resistant Klebsiella pneumoniae in Central South China: a multicenter study.
Tracking clonal and plasmid transmission in colistin- and carbapenem-resistant Klebsiella pneumoniae.
mutation in pmrB gene confers colistin resistance
From genomics to treatment: overcoming pan-drug-resistant Klebsiella pneumoniae in clinical settings.
Molecular Analysis of Polymyxin Resistance among Carbapenemase-Producing Klebsiella pneumoniae in Colombia.
Mutations in pmrB
Aerobactin Seems To Be a Promising Marker Compared With Unstable RmpA2 for the Identification of Hypervirulent Carbapenem-Resistant Klebsiella pneumoniae: In Silico and In Vitro Evidence.
mutation in pmrB leads to colistin resistance
Molecular Mechanisms of Colistin Resistance in Klebsiella pneumoniae in a Tertiary Care Teaching Hospital.
Polymyxin-resistant hypervirulent Klebsiella pneumoniae clinical isolates from a tertiary hospital in China: molecular mechanisms, antimicrobial susceptibility, and virulent phenotypes.
Identified in the study and consistent with previous research.
Characterization of Metallo β-Lactamase Producing Enterobacterales Isolates with Susceptibility to the Aztreonam/Avibactam Combination.
In-depth characterization of multidrug-resistant NDM-1 and KPC-3 co-producing Klebsiella pneumoniae bloodstream isolates from Italian hospital patients.
Clonal transmission of polymyxin B-resistant hypervirulent Klebsiella pneumoniae isolates coharboring bla(NDM-1) and bla(KPC-2) in a tertiary hospital in China.
Detection of maternal transmission of resistant Gram-negative bacteria in a Cambodian hospital setting.
Not considered as colistin resistant as per previous studies
Molecular mechanisms of colistin- and multidrug-resistance in bacteria among patients with hospital-acquired infections.
mutations in pmrB gene contribute to colistin resistance
High prevalence of mgrB-mediated colistin resistance among carbapenem-resistant Klebsiella pneumoniae is associated with biofilm formation, and can be overcome by colistin-EDTA combination therapy.
mutations in pmrB contribute to colistin resistance
Polymyxin Resistance in Clinical Isolates of K. pneumoniae in Brazil: Update on Molecular Mechanisms, Clonal Dissemination and Relationship With KPC-Producing Strains.
Characterization of Carbapenemase-Producing Klebsiella pneumoniae Isolates from Two Romanian Hospitals Co-Presenting Resistance and Heteroresistance to Colistin.
Mutations in pmrB were observed in multiple strains and are associated with colistin resistance
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