Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
VanD-Type Vancomycin-Resistant Enterococcus faecium and Enterococcus faecalis.
Mutations in ddl impair d-Ala:d-Ala ligase activity, leading to reduced peptidoglycan precursor synthesis and vancomycin resistance.
Sequencing of the ddl gene and modeling of the mutated D-alanine:D-alanine ligase in glycopeptide-dependent strains of Enterococcus faecium.
D-Ala-D-Ala ligase; CARD accession: CARD:3003970
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