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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations rpoBR484C

GenerpoB

Protein ChangeR484C

Nucleotide ChangeC1462T

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogReslit

Overview

Mechanism: DNA-directed RNA polymerase subunit beta RpoB
Resistance To: Rifampin, RIFAMPIN
Organisms: Staphylococcus aureus
Papers: 1

Paper Information1

1

In vitro activity of novel rifamycins against rifamycin-resistant Staphylococcus aureus.

PMID 16495239 · 2006

Mutations in rpoB confer resistance to rifampin.

Mutation Information

rpoB: p.R484C / c.C1462T

Protein Change: R484C
Nucleotide Change: C1462T
Organisms: Staphylococcus aureus
Confers Resistance To

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Rifampin

Source Database

Reslit

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research