ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeF227L

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: F227L are on the outer surface adjacent to the tRNA molecule about 20 Å from the editing active site
Resistance To: Mupirocin
Organisms: Staphylococcus aureus
Papers: 1

Paper Information1

Molecular analysis of isoleucyl-tRNA synthetase mutations in clinical isolates of methicillin-resistant Staphylococcus aureus with low-level mupirocin resistance.

PMID 17043414 · 2006

All mutations were identified in low-level mupirocin-resistant MRSA isolates.

Mutation Information

ileS: p.F227L

Protein Change: F227L
Organisms: Staphylococcus aureus
Confers Resistance To

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Mutation Information