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Browse Mutations pmrBL243R

GenepmrB

Protein ChangeL243R

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: confers resistance to colistin
Resistance To: colistin
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

1

The Essential Role of Hypermutation in Rapid Adaptation to Antibiotic Stress.

Research Article

PMID 31036684 · 2019

Mutations in pmrB contribute to colistin resistance.

Mutation Information

Protein Change: L243R
Organisms: Pseudomonas aeruginosa
Confers Resistance To: colistin
Effect on Function: confers resistance to colistin
Validation Method: genomic analysis and allelic replacement
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
GitHub
Zenodo archive
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research