ResLit - Antimicrobial Resistance Gene & Mutation Database

GeneacrA

multidrug efflux pump

Protein ChangeG240S

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Novobiocin|Lincomycin
Organisms: Escherichia coli
Papers: 1

Paper Information1

Fitting periplasmic membrane fusion proteins to inner membrane transporters: mutations that enable Escherichia coli AcrA to function with Pseudomonas aeruginosa MexB.

PMID 18024521 · 2008

Mutations in AcrA improve the functional fit with MexB, enabling resistance to various antibiotics.

Mutation Information

acrA: p.G240S

Protein Change: G240S
Organisms: Escherichia coli
Confers Resistance To: Novobiocin|Lincomycin
Source Database: Reslit

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