Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
A Narrative Review of Bedaquiline and Delamanid: New Arsenals Against Multidrug-Resistant and Extensively Drug-Resistant Mycobacterium tuberculosis.
Review
Mutations in atpE are associated with BDQ resistance.
In vitro Study of Bedaquiline Resistance in Mycobacterium tuberculosis Multi-Drug Resistant Clinical Isolates.
Research Article
A novel one-tube nested fluorescence melting curve analysis for rapid detection of drug-resistant Mycobacterium tuberculosis.
Research Article
All mutations were confirmed by DNA sequencing.
Validation of Bedaquiline Phenotypic Drug Susceptibility Testing Methods and Breakpoints: a Multilaboratory, Multicountry Study.
Research Article
Clofazimine Exposure In Vitro Selects Efflux Pump Mutants and Bedaquiline Resistance
Research Article
Mutations in atpE are associated with bedaquiline resistance, but not with clofazimine resistance.
Empirical ways to identify novel Bedaquiline resistance mutations in AtpE.
Research Article
These mutations were identified as resistance-associated variants through structural and functional analysis.
Designing molecular diagnostics for current tuberculosis drug regimens.
Research Article
Bedaquiline and clofazimine resistance in Mycobacterium tuberculosis: an in-vitro and in-silico data analysis.
Research Article
Variants in atpE are associated with bedaquiline resistance.
Bedaquiline for treatment of non-tuberculous mycobacteria (NTM): a systematic review and meta-analysis.
Review
Molecular Targets Related Drug Resistance Mechanisms in MDR-, XDR-, and TDR-Mycobacterium tuberculosis Strains.
Review
A63P mutation in atpE is associated with resistance to BDQ.
Systematic review of mutations associated with resistance to the new and repurposed Mycobacterium tuberculosis drugs bedaquiline, clofazimine, linezolid, delamanid and pretomanid.
Review
At least 4-fold increase in bedaquiline MIC
Mycobacterium tuberculosis atpE with mutation conferring resistance to bedaquiline; CARD accession: CARD:3007854
Bedquiline Resistance Mutations: Correlations with Drug Exposures and Impact on the Proteome in M. tuberculosis.
Research Article
mutations in atpE are associated with high-level bedaquiline resistance
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