ResLit - Antimicrobial Resistance Gene & Mutation Database

GenemutS

DNA mismatch repair protein

Protein ChangeS31G

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: amikacin, piperacillin tazobactam, ceftazidime
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

The role of hypermutation and collateral sensitivity in antimicrobial resistance diversity of Pseudomonas aeruginosa populations in cystic fibrosis lung infection.

Research Article

PMID 38171021 · 2024

Mutations in mutS contribute to hypermutation and increased susceptibility to certain antibiotics.

Mutation Information

mutS: p.S31G

Protein Change: S31G
Organisms: Pseudomonas aeruginosa
Confers Resistance To: amikacinpiperacillin tazobactamceftazidime
Validation Method: SNP analysis and zone of inhibition measurements
Source Database: Reslit

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