ResLit - Antimicrobial Resistance Gene & Mutation Database

GenelpsB

Intrinsic peptide antibiotic resistant Lps

Protein ChangeH181Y

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: polymyxin b, polymyxins
Organisms: Acinetobacter baumannii
Papers: 2

Paper Information2

Prevalence and Genetic Characterization of Carbapenem- and Polymyxin-Resistant Acinetobacter baumannii Isolated from a Tertiary Hospital in Terengganu, Malaysia.

Research Article

PMID 25006521 · 2014

Mutation Information

lpsB: p.H181Y

Protein Change: H181Y
Organisms: Acinetobacter baumannii
Confers Resistance To: polymyxin b
Validation Method: sequencing of lpsB gene
Source Database: Reslit

Comparative Genomics of Two ST 195 Carbapenem-Resistant Acinetobacter baumannii with Different Susceptibility to Polymyxin Revealed Underlying Resistance Mechanism.

Research Article

PMID 26779129 · 2015

Mutations in lpsB gene contribute to polymyxin resistance in AC30.

Mutation Information

lpsB: p.H181Y

Protein Change: H181Y
Organisms: Acinetobacter baumannii
Confers Resistance To: polymyxin bpolymyxins
Validation Method: Genome analysis; H181Y substitution in lpsB of AC30
Source Database: Reslit

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