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Browse Mutations Rv0678N98D

protein

Protein ChangeN98D

Nucleotide ChangeA293G

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Bedaquiline|Clofazimine
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

1

MDR M. tuberculosis outbreak clone in Eswatini missed by Xpert has elevated bedaquiline resistance dated to the pre-treatment era.

PMID 33239092 · 2020

Mutations in Rv0678 correlate with elevated MICs to bedaquiline and clofazimine.

Mutation Information

Rv0678: p.N98D / c.A293G

Protein Change: N98D
Nucleotide Change: A293G
Organisms: Mycobacterium tuberculosis

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Confers Resistance To

Bedaquiline|Clofazimine

Source Database

Reslit

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research