ResLit - Antimicrobial Resistance Gene & Mutation Database

beta-lactamase

Nucleotide ChangeC-42G

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogResFinder Database

Overview

Mechanism: Enzymatic degradation, ampC/blaEC promoter region
Resistance To: ampicillin, ampicillin clavulanic acid, amoxicillin, amoxicillin clavulanic acid, cefixime, cefotaxime, cefoxitin, ceftazidime, piperacillin, cephalosporins
Organisms: Escherichia coli
Papers: 2

Paper Information2

Detection of AmpC beta-lactamase in Escherichia coli: comparison of three phenotypic confirmation assays and genetic analysis.

Research Article

ampC

Nucleotide Change: C-42G
Organisms: Escherichia coli
Confers Resistance To: ampicillinampicillin clavulanic acidamoxicillinamoxicillin clavulanic acidcefiximecefotaximecefoxitinceftazidimepiperacillincephalosporins
Effect on Function: Enzymatic degradation; ampC/blaEC promoter region
Source Database: ResFinder DatabaseReference Gene Catalog

The E. coli beta-lactamase attenuator mediates growth rate-dependent regulation.

Research Article

ampC

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