ResLit - Antimicrobial Resistance Gene & Mutation Database

GenefusA1

Protein ChangeQ678L

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogReslit

Overview

Mechanism: elongation factor G FusA1
Resistance To: tobramycin, amikacin
Organisms: Pseudomonas aeruginosa, Acinetobacter baumannii
Papers: 2

Paper Information2

Parallel Evolution of Tobramycin Resistance across Species and Environments.

Research Article

PMID 32457248 · 2020

Mutations in fusA1 were found in both A. baumannii and P. aeruginosa, contributing to tobramycin resistance.

Mutation Information

fusA1: p.Q678L

Protein Change: Q678L
Organisms: Pseudomonas aeruginosa, Acinetobacter baumannii
Confers Resistance To: tobramycin
Validation Method: MIC measurements
Source Database: Reslit

A large-scale whole-genome comparison shows that experimental evolution in response to antibiotics predicts changes in naturally evolved clinical Pseudomonas aeruginosa.

Research Article

PMID 31570397 · 2019

fusA1

Mutation Information

fusA1: p.Q678L

Protein Change: Q678L
Organisms: Pseudomonas aeruginosa
Confers Resistance To: amikacintobramycin
Effect on Function: elongation factor G FusA1
Source Database: Reference Gene Catalog

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