Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Variants associated with Bedaquiline (BDQ) resistance identified in Rv0678 and efflux pump genes in Mycobacterium tuberculosis isolates from BDQ naïve TB patients in Pakistan.
variants in Rv0678 gene are associated with BDQ resistance
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Clofazimine Exposure In Vitro Selects Efflux Pump Mutants and Bedaquiline Resistance
Mutations in rv0678 lead to overexpression of the mmpL5-mmpS5 efflux pump, causing cross-resistance to bedaquiline and clofazimine.
Bedaquiline and clofazimine resistance in Mycobacterium tuberculosis: an in-vitro and in-silico data analysis.
Mutations in Rv0678 are associated with bedaquiline and clofazimine resistance.
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