Unknown
T83I
Gene: gyrA
Curation StatusNot Validated
Overview
- Resistance To
- moxifloxacin
- Organisms
- Clostridium difficile
- Paper
- 1
Paper Information1
1
Resistance to moxifloxacin in toxigenic Clostridium difficile isolates is associated with mutations in gyrA.
PMID 11451695 · 2001Thirteen isolates showed the same nucleotide transition (ACT→ATT) resulting in a threonine→isoleucine change. In one isolate (1542), two nucleotide changes (ACT→GTT) resulted in a replacement of threonine by valine.
Mutation Information
- Gene Name
- gyrA
- Protein Change
- T83I
Confers Resistance To
moxifloxacin
Organisms Observed In
• Clostridium difficile
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