ResLit - Antimicrobial Resistance Gene & Mutation Database

GeneampC

beta-lactamase

Protein ChangeQ86L

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: derepression of AmpC
Resistance To: Cefoxitin|Cefotaxime|Cefepime|Ertapenem|Imipenem|Meropenem
Organisms: Enterobacter cloacae
Papers: 1

Paper Information1

Association of Novel Nonsynonymous Single Nucleotide Polymorphisms in ampD with Cephalosporin Resistance and Phylogenetic Variations in ampC, ampR, ompF, and ompC in Enterobacter cloacae Isolates That Are Highly Resistant to Carbapenems.

PMID 26856839 · 2016

Amino acid substitution in AmpD that distinguishes NCTC 13405 from NCTC 13406

Mutation Information

ampC: p.Q86L

Protein Change: Q86L
Organisms: Enterobacter cloacae
Confers Resistance To

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Mutation Information