Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
parC Variants in Mycoplasma genitalium: Trends over Time and Association with Moxifloxacin Failure.
The mutation G248T in parC leads to the amino acid change S83I, which is associated with moxifloxacin failure.
Molecular detection of Mycoplasma genitalium in endocervical swabs and associated rates of macrolide and fluoroquinolone resistance in Hong Kong.
Mycoplasma genitalium Antimicrobial Resistance in Community and Sexual Health Clinic Patients, Auckland, New Zealand.
Mutations in codon 83 of parC are associated with resistance; therefore, the mutation at T249A was presumed to confer fluoroquinolone resistance. The importance of polymorphisms in parC at C184T and C356T is uncertain.
Clinical Performance of Three Commercial Molecular Diagnostic Assays for the Detection of Fluoroquinolone Resistance-Associated Mutations in Mycoplasma genitalium.
Mutations in the parC gene were associated with fluoroquinolone resistance.
Effectiveness of sitafloxacin monotherapy for quinolone-resistant rectal and urogenital Mycoplasma genitalium infections: a prospective cohort study.
Efficacy of Sitafloxacin for Mycoplasma genitalium in an Era of Increasing Antimicrobial Resistance.
The study suggests that parC mutations, particularly G248T leading to S83I, are associated with reduced susceptibility to fluoroquinolones.
No comments yet. Be the first to comment!
© 2026 ResLit. Data sourced from PubMed literature analysis.
Built for antimicrobial resistance research