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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations sigAG336C

GenesigA

primary sigma factor of RNA polymerase

Protein ChangeG336C

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: reduces susceptibility to vancomycin and fosfomycin by altering promoter recognition.
Resistance To: Vancomycin|Fosfomycin
Organisms: Bacillus subtilis
Papers: 1

Paper Information1

1

Mutations in the Primary Sigma Factor σA and Termination Factor Rho That Reduce Susceptibility to Cell Wall Antibiotics.

PMID 25112476 · 2014

The sigA G336C mutation reduces susceptibility to vancomycin and fosfomycin by altering promoter recognition.

Mutation Information

Protein Change: G336C
Organisms: Bacillus subtilis
Confers Resistance To

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Vancomycin|Fosfomycin

Effect on Function

reduces susceptibility to vancomycin and fosfomycin by altering promoter recognition.

Source Database

Reslit

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research