Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
A Narrative Review of Bedaquiline and Delamanid: New Arsenals Against Multidrug-Resistant and Extensively Drug-Resistant Mycobacterium tuberculosis.
Mutations in atpE are associated with BDQ resistance.
High Prevalence of atpE Mutations in Bedaquiline-Resistant Mycobacterium tuberculosis Isolates, Russia.
mutations in atpE are associated with bedaquiline resistance
Identification of genetic determinants of bedaquiline resistance in Mycobacterium tuberculosis in Ural region, Russia.
associated with resistance-interim
A novel one-tube nested fluorescence melting curve analysis for rapid detection of drug-resistant Mycobacterium tuberculosis.
All mutations were confirmed by DNA sequencing.
Empirical ways to identify novel Bedaquiline resistance mutations in AtpE.
These mutations were identified as resistance-associated variants through structural and functional analysis.
Bedaquiline for treatment of non-tuberculous mycobacteria (NTM): a systematic review and meta-analysis.
Systematic review of mutations associated with resistance to the new and repurposed Mycobacterium tuberculosis drugs bedaquiline, clofazimine, linezolid, delamanid and pretomanid.
At least 4-fold increase in bedaquiline MIC
Mycobacterium tuberculosis atpE with mutation conferring resistance to bedaquiline; CARD accession: CARD:3007854
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