Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Cephalosporin and ciprofloxacin resistance in Salmonella, Taiwan.
Mutation in parC contributes to ciprofloxacin resistance
Genetic analysis of a multiresistant strain of Pseudomonas aeruginosa producing PER-1 beta-lactamase.
mutations in the quinolone resistance-determining regions of gyrA and parC
Genetic basis of multidrug resistance in Acinetobacter baumannii clinical isolates at a tertiary medical center in Pennsylvania.
Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City.
Insights into the Environmental Resistance Gene Pool from the Genome Sequence of the Multidrug-Resistant Environmental Isolate Escherichia coli SMS-3-5
ParC mutations confer resistance to ciprofloxacin in combination with at least one mutation in gyrA.
Phenotypic and molecular characterization of Acinetobacter baumannii clinical isolates from nosocomial outbreaks in Los Angeles County, California.
Molecular Diagnostic Technologies in Clinical Microbiology
The prevalence of fluoroquinolone resistance mechanisms in colonizing Escherichia coli isolates recovered from hospitalized patients.
Alterations of gyrA, gyrB, and parC and Activity of Efflux Pump in Fluoroquinolone-resistant Acinetobacter baumannii.
Mutation S80L in parC was observed in some isolates.
A Large-Scale Whole-Genome Comparison Shows that Experimental Evolution in Response to Antibiotics Predicts Changes in Naturally Evolved Clinical Pseudomonas aeruginosa.
Genomic Characterization of Extensively Drug-Resistant NDM-Producing Acinetobacter baumannii Clinical Isolates With the Emergence of Novel bla (ADC-257).
Molecular mechanisms impact on fluoroquinolone resistance among E.coli from enteric carriage monitoring before prostate biopsy and earliest description of qnrB81.
Mutations in the QRDR of parC contribute to fluoroquinolone resistance.
Species Distribution, Antimicrobial Resistance, and Enterotoxin Profiles of Non-aureus Staphylococci Isolated from Poultry Slaughterhouses in Korea.
Molecular epidemiology of extended-spectrum beta-lactamase-producing, fluoroquinolone-resistant isolates of Klebsiella pneumoniae in Taiwan.
Mutations in parC were associated with quinolone resistance in K. pneumoniae isolates.
Time-kill curve analysis and pharmacodynamic modelling for in vitro evaluation of antimicrobials against Neisseria gonorrhoeae.
Mutations in parC were identified in WHO reference strains and contributed to ciprofloxacin resistance.
Genomic Analysis of Carbapenem-Resistant Acinetobacter baumannii Isolates Belonging to Major Endemic Clones in South America.
Overexpression of Efflux Pumps, Mutations in the Pumps' Regulators, Chromosomal Mutations, and AAC(6′)-Ib-cr Are Associated With Fluoroquinolone Resistance in Diverse Sequence Types of Neonatal Septicaemic Acinetobacter baumannii: A 7-Year Single Center Study.
Chromosomal mutations in ParC contribute to fluoroquinolone resistance
Prevalence and Characterization of Quinolone-Resistance Determinants in Escherichia coli Isolated from Food-Producing Animals and Animal-Derived Food in the Philippines.
Mechanisms of fluoroquinolone resistance among Escherichia coli isolates from urinary tract infections in Thailand.
Integrative review on Acinetobacter baumannii as a multidrug-resistant pathogen: resistance mechanisms and therapeutic perspectives in the context of nosocomial infections.
Emerging nalidixic acid and ciprofloxacin resistance in non-typhoidal Salmonella isolated from patients having acute diarrhoeal disease.
Mutations in parC were associated with nalidixic acid and ciprofloxacin resistance.
Characterization of antimicrobial-resistant Salmonella isolated from imported foods.
The Acinetobacter baumannii Oxymoron: Commensal Hospital Dweller Turned Pan-Drug-Resistant Menace.
Mutations in parC are often accompanied by mutations in gyrA.
Current Evidence for Corynebacterium on the Ocular Surface.
Mutations in parC contribute to fluoroquinolone resistance in Corynebacterium species.
Genomic Insights into bla(NDM-5)-Producing Escherichia coli ST648 Isolates from Human and Wildlife Sources in Lebanon.
A first look into the genomic characterization and fluoroquinolone resistance genotypes of Mycoplasma spp. in Colombian poultry.
Mutation detected in MG field strains.
Antibiotic resistance determinants of a group of multidrug-resistant Acinetobacter baumannii in China.
mutation in QRDR of parC
Detection of quinolone-resistance mutations of parC gene in clinical isolates of Acinetobacter baumannii in Iran.
Mutations in parC gene associated with quinolone resistance
Association between mutations in gyrA and parC genes of Acinetobacter baumannii clinical isolates and ciprofloxacin resistance.
Observation of a new pattern of mutations in gyrA and parC within Escherichia coli exhibiting fluroquinolone resistance.
Molecular characterization and antimicrobial susceptibility of Acinetobacter baumannii isolates obtained from two hospital outbreaks in Los Angeles County, California, USA.
A Novel Mismatched PCR-Restriction Fragment Length Polymorphism Assay for Rapid Detection of gyrA and parC Mutations Associated With Fluoroquinolone Resistance in Acinetobacter baumannii.
Detected in 45 out of 47 FQ-resistant strains
Bimodal Actions of a Naphthyridone/Aminopiperidine-Based Antibacterial That Targets Gyrase and Topoisomerase IV.
Mutation in ParC (S80L) confers resistance to fluoroquinolones.
Antimicrobial susceptibility pattern of Acinetobacter isolates from patients in Kenyatta National Hospital, Nairobi, Kenya.
High levels of multiresistance in quinolone resistant urinary tract isolates of Escherichia coli from Norway; a non clonal phenomenon?
Mutations in parC were associated with quinolone resistance.
An outbreak of blaOXA-51-like- and blaOXA-66-positive Acinetobacter baumannii ST208 in the emergency intensive care unit.
Mutations in parC contribute to quinolone resistance
Role of the water-metal ion bridge in mediating interactions between quinolones and Escherichia coli topoisomerase IV.
Mutations in ParC affect ciprofloxacin binding and activity
Antimicrobial Resistance in Acinetobacter spp. and Pseudomonas spp.
Genomic epidemiology of severe community-onset Acinetobacter baumannii infection.
DNA microarray for genotyping antibiotic resistance determinants in Acinetobacter baumannii clinical isolates.
ParC S80L mutation confers resistance to ciprofloxacin.
Genome-resolved insight into the reservoir of antibiotic resistance genes in aquatic microbial community.
The resistance mechanisms of bacteria against ciprofloxacin and new approaches for enhancing the efficacy of this antibiotic.
Rapid emergence of extensively drug-resistant Shigella sonnei in France.
Species Profiles and Antimicrobial Resistance of Non-aureus Staphylococci Isolated from Healthy Broilers, Farm Environments, and Farm Workers.
Strain belonging to an emerging, virulent sublineage of ST131 Escherichia coli isolated in fresh spinach, suggesting that ST131 may be transmissible through agricultural products.
A Review of the Resistance Mechanisms for β-Lactams, Macrolides and Fluoroquinolones among Streptococcus pneumoniae.
Risk factors and clinical significance of invasive infections caused by levofloxacin-resistant Streptococcus pneumoniae.
Single point mutation in parC gene responsible for levofloxacin resistance.
Mutations in the quinolone resistance-determining regions of gyrA and parC in Enterobacteriaceae isolates from Brazil.
Mutations in parC gene are associated with fluoroquinolone resistance.
Comparative Genomics of Two ST 195 Carbapenem-Resistant Acinetobacter baumannii with Different Susceptibility to Polymyxin Revealed Underlying Resistance Mechanism.
Mutation in parC contributes to fluoroquinolone resistance.
Zinc can counteract selection for ciprofloxacin resistance.
Spontaneously mutated ciprofloxacin-resistant strain was created through serial inoculation of overnight culture in LB medium supplemented with incremental concentrations of ciprofloxacin.
Gold nanocluster adjuvant enables the eradication of persister cells by antibiotics and abolishes the emergence of resistance.
Mutation in parC was identified as the resistance mechanism in PA01 after exposure to sub-MIC of OFL.
Topoisomerase IV is a target of quinolones in Escherichia coli.
parC
Unknown phenotype if each mutation occurs alone. Nalidixic acid and ciprofloxacin resistance when associated with gyrA mutations
gyrA and parC mutations in quinolone-resistant clinical isolates of Pseudomonas aeruginosa from Nini Hospital in north Lebanon.
Pseudomonas aeruginosa gyrA and parC conferring resistance to fluoroquinolones; CARD accession: CARD:3003702
Unknown phenotype if each mutation occurs alone. Nalidixic acid and ciprofloxacin resistance when associated with gyrA mutations
Characterisation of novel mutations involved in quinolone resistance in Escherichia coli isolated from imported shrimp.
Unknown phenotype if each mutation occurs alone. Nalidixic acid and ciprofloxacin resistance when associated with gyrA mutations
Quinolone-resistant mutants of escherichia coli DNA topoisomerase IV parC gene.
Unknown phenotype if each mutation occurs alone. Nalidixic acid and ciprofloxacin resistance when associated with gyrA mutations
Mechanisms accounting for fluoroquinolone resistance in Escherichia coli clinical isolates.
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