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Browse Mutations blaOXY-2D197N

Protein ChangeD197N

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: enhanced hydrolytic activity against monobactams
Organisms: Klebsiella oxytoca
Papers: 1

Paper Information1

1

The extended-spectrum K1 beta-lactamase from Klebsiella oxytoca SC 10,436 is a member of the bla(OXY-2) family of chromosomal Klebsiella enzymes.

PMID 12019142 · 2002

The promoter region mutations enhance hydrolytic activity against monobactams.

Mutation Information

blaOXY-2: p.D197N

Protein Change: D197N
Organisms: Klebsiella oxytoca
Effect on Function: enhanced hydrolytic activity against monobactams
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research