ResLit - Antimicrobial Resistance Gene & Mutation Database

GeneethA

FAD-containing monooxygenase

Protein ChangeL440P

Nucleotide Change880fs

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Ethionamide|Perchlozone
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

Perchlozone Resistance in Clinical Isolates of Mycobacterium tuberculosis.

PMID 36978456 · 2023

Two samples with mutations in ethA and a high MIC of perchlozone (16 and 32 mg/L) retained a low MIC of ethionamide of 0.6 and 2.5 mg/L, which were below the breakpoint.

Mutation Information

ethA: p.L440P / c.880fs

Protein Change: L440P
Nucleotide Change: 880fs
Organisms: Mycobacterium tuberculosis

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Mutation Information