ResLit - Antimicrobial Resistance Gene & Mutation Database

GeneethA

FAD-containing monooxygenase

Nucleotide ChangeT-11C

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: reduced transcription
Resistance To: Ethionamide
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

Whole-Transcriptome and -Genome Analysis of Extensively Drug-Resistant Mycobacterium tuberculosis Clinical Isolates Identifies Downregulation of ethA as a Mechanism of Ethionamide Resistance.

PMID 28993337 · 2017

mutation in promoter region of ethA

Mutation Information

ethA: c.T-11C

Nucleotide Change: T-11C
Organisms: Mycobacterium tuberculosis
Confers Resistance To

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Mutation Information