ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeM112I

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: partially recovered the ability to copurify with LptC
Resistance To: Bacitracin
Organisms: Escherichia coli
Papers: 1

Paper Information1

Mutation and Suppressor Analysis of the Essential Lipopolysaccharide Transport Protein LptA Reveals Strategies To Overcome Severe Outer Membrane Permeability Defects in Escherichia coli.

PMID 29109183 · 2018

The lptA42 allele encodes an additional amino acid change (M112I) in LptA41, which partially recovered the ability to copurify with LptC.

Mutation Information

lptA: p.M112I

Protein Change: M112I
Organisms: Escherichia coli
Confers Resistance To

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Mutation Information