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Browse Mutations Rv0678G296T

protein

Protein ChangeG296T

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Clofazimine|Bedaquiline
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

1

Molecular Targets Related Drug Resistance Mechanisms in MDR-, XDR-, and TDR-Mycobacterium tuberculosis Strains.

PMID 29755957 · 2018

Mutation in Rv0678 upregulates MmpL5, contributing to resistance to CLO and BDQ.

Mutation Information

Rv0678: p.G296T

Protein Change: G296T
Organisms: Mycobacterium tuberculosis
Confers Resistance To: Clofazimine|Bedaquiline
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research