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Browse Mutations folAN147D

GenefolA

Protein ChangeN147D

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: resistance
Resistance To: Trimethoprim
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Directed evolution of multiple genomic loci allows the prediction of antibiotic resistance.

PMID 29871954 · 2018

Mutations in folA were identified as conferring resistance to trimethoprim.

Mutation Information

Protein Change: N147D
Organisms: Escherichia coli
Confers Resistance To: Trimethoprim

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Effect on Function

resistance

Source Database

Reslit

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research