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Browse Mutations aac(6')-Ib-crL119S

Geneaac(6')-Ib-cr

aminoglycoside acetyltransferase

Protein ChangeL119S

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: loss of amikacin resistance while causing resistance to gentamicin
Resistance To: Gentamicin
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Genotypic characterization of multiple drug resistant Escherichia coli isolates from a pediatric cancer hospital in Egypt.

PMID 32139767 · 2020

Leu119Ser mutation associated with loss of amikacin resistance and resistance to gentamicin

Mutation Information

aac(6')-Ib-cr: p.L119S

Protein Change: L119S
Organisms: Escherichia coli
Confers Resistance To

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Gentamicin

Effect on Function

loss of amikacin resistance while causing resistance to gentamicin

Source Database

Reslit

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research