ResLit - Antimicrobial Resistance Gene & Mutation Database

GeneacrB

subunit of the AcrAB-TolC efflux pump

Protein ChangeR620S

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: hypersusceptibility toward ampicillin and colistin
Resistance To: Chloramphenicol|Ampicillin
Organisms: Salmonella typhimurium
Papers: 1

Paper Information1

Loss of the Periplasmic Chaperone Skp and Mutations in the Efflux Pump AcrAB-TolC Play a Role in Acquired Resistance to Antimicrobial Peptides in Salmonella typhimurium.

PMID 32210923 · 2020

Mutation Information

acrB: p.R620S

Protein Change: R620S
Organisms: Salmonella typhimurium
Confers Resistance To: Chloramphenicol|Ampicillin

Browse AMR Mutations

Mutation Information