Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
A novel one-tube nested fluorescence melting curve analysis for rapid detection of drug-resistant Mycobacterium tuberculosis.
All mutations were confirmed by DNA sequencing.
Clofazimine Exposure In Vitro Selects Efflux Pump Mutants and Bedaquiline Resistance
Mutations in atpE are associated with bedaquiline resistance, but not with clofazimine resistance.
In Vitro Study of Stepwise Acquisition of rv0678 and atpE Mutations Conferring Bedaquiline Resistance.
Emergence of Canonical and Noncanonical Genomic Variants following In Vitro Exposure of Clinical Mycobacterium tuberculosis Strains to Bedaquiline or Clofazimine.
variants in atpE were identified in bedaquiline-resistant mutants
Bedaquiline and clofazimine resistance in Mycobacterium tuberculosis: an in-vitro and in-silico data analysis.
Variants in atpE are associated with bedaquiline resistance.
Bedaquiline for treatment of non-tuberculous mycobacteria (NTM): a systematic review and meta-analysis.
Systematic review of mutations associated with resistance to the new and repurposed Mycobacterium tuberculosis drugs bedaquiline, clofazimine, linezolid, delamanid and pretomanid.
At least 4-fold increase in bedaquiline MIC
Mycobacterium tuberculosis atpE with mutation conferring resistance to bedaquiline; CARD accession: CARD:3007854
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